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| Product Name | IL-4, Recombinant, Human (BCGF, BCDF, B cell stimulating factor (BSF-1)) |
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| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression.Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response.Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes.Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy.Recombinant human IL-4 is a 15.1kD globular protein containing 130 amino acid residues. Biological Activity: The ED50 as determined by the dose-dependent stimulation of human TF-1 cells is ~0.2ng/ml, corresponding to a specific activity of ~5x10e6 units/mg. AA Sequence: MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIF |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143409 |
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| Order / More Info | IL-4, Recombinant, Human (BCGF, BCDF, B cell stimulating factor (BSF-1)) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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