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| Product Name | IL-34, Recombinant, Human (C16orf77) |
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| Description | Purity ≥95% by SDS-PAGE gel and HPLC analyses. IL-34 is a homodimeric cytokine that is expressed in a range of tissues including spleen, heart, brain, liver, kidney, lung, ovary, thymus, testis, small intestine, prostate and colon.IL-34 is a ligand for colony-stimulating factor-1 receptor (CSF1R), which also binds to CSF-1.It specifically binds CD14+ monocytes, promotes survival and proliferation of human peripheral blood monocytes, and stimulates macrophage colony formation by human bone marrow cells.IL-34, like human CSF-1 stimulates phosphorylation of MAPK1/ERK2 and MAPK3/ERK1.Recombinant human IL-34 is a 52.5kD homodimeric glycoprotein consisting of 460 amino acid residues, including a C-terminal His-Tag. Biological Activity: Measured by its ability to induce secretion of MCP-1 from PBMCs. AA Sequence: NEPLEMWPLT QNEECTVTGF LRDKLQYRSR LQYMKHYFPI NYKISVPYEG VFRIANVTRL QRAQVSEREL RYLWVLVSLS ATESVQDVLL EGHPSWKYLQ EVETLLLNVQ QGLTDVEVSP KVESVLSLLN APGPNLKLVR PKALLDNCFR VMELLYCSCC KQSSVL |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143404 |
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| Order / More Info | IL-34, Recombinant, Human (C16orf77) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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