| 产品名称 |
IL10, Recombinant, Human (IL-10, Cytokine Synthesis Inhibitory Factor, CSIF, B-TCGF, TGIF, Interleukin-10) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | IL10, Recombinant, Human (IL-10, Cytokine Synthesis Inhibitory Factor, CSIF, B-TCGF, TGIF, Interleukin-10) |
| Description | Purity ~95% (SDS-PAGE). IL-10 is produced by mouse Th2 cells following their stimulation by lectins. The main source for B cell derived IL-10 in mice are Ly1 B cells that express CD5 (Ly1) and CD11. In humans IL-10 is produced by activated CD8(+) peripheral blood T cells, by T helper CD4(+) T cell clones after both antigen-specific and polyclonal activation, by B cell lymphomas, and by monocytes following cell activation by bacterial lipopolysaccharides and mast cells. IL-10 is a homodimeric protein with subunits having a length of 160 amino acids. Human Interleukin-10 shows 73% amino acid homology with mouse Interleukin-10. The murine IL-10 receptor has been cloned. This receptor is a protein of approximately 110 kDa that binds murine IL-10 specifically. This receptor is structurally related to receptors for IFN. The CD nomenclature for this receptor is CDw210. IL-10 inhibits the synthesis of a number of cytokines such as IFN-gamma, IL-2 and TNF-beta in Th1 T helper subpopulations of T cells but not of Th2 T |
| Size | 25ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | n/a |
| Gene, Accession, CAS # | SwissProt: P22301 |
| Catalog # | 500097 |
| Price | |
| Order / More Info | IL10, Recombinant, Human (IL-10, Cytokine Synthesis Inhibitory Factor, CSIF, B-TCGF, TGIF, Interleukin-10) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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