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| Product Name | IL20, Recombinant, Human (IL-20, Cytokine Zcyto10, ZCYTO10, Interleukin-20) |
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| Description | Purity ~95% (SDS-PAGE). IL-19 and IL-20 are mainly produced by activated monocytes, IL-24 is produced by Th2 cells, monocytes, and melanocytic cells, and IL-22 and IL-26 are primarily produced by activated T cells. Like IL-10, these class II cytokines signal through heterodimeric receptors. Overexpression of IL-20 in transgenic mice causes neonatal death as well as skin abnormalities, including aberrant epidermal differentiation. IL-20 selectively enhances multipotential hematopoietic progenitors in vitro and in vivo. IL-20 is preferentially expressed in monocytes18 and induces STAT 3 activation through binding to two types of IL-20 receptor (R) complexes, either IL-20R1/IL-20R2 or IL-22R1/IL-20R2. Source: Recombinant protein corresponding to human IL20 expressed in E. coli. Molecular Weight: ~16kD Biological Activity: The ED50 was determined by by a cell proliferation assay using human IL-20R-alpha and human IL-20R-beta co-transfected murine BaF3 pro-B cells, and was found to be ≤0.6ng/ml. Specific Activity: |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q9NYY1 |
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| Catalog # | 500134 |
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| Order / More Info | IL20, Recombinant, Human (IL-20, Cytokine Zcyto10, ZCYTO10, Interleukin-20) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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