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| Product Name | IL-4, Recombinant, Mouse |
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| Description | Purity ~98% (SDS-PAGE, HPLC). IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant mouse IL-4 is a globular protein containing 120aa residues. Source: Recombinant protein corresponding to mouse IL-4, expressed in E. coli. Molecular Weight: ~13.5kD Biological Activity: The ED50, determined by the dose-dependent stimulation of the proliferation of murine HT-2 cells, is <.2.0ng correspond> |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL-4, Recombinant, Mouse (Interleukin 4, BCGF, BCDF, B Cell Stimulating Factor, BSF-1, Lymphocyte Stimulatory Factor 1, MGC79402, Binetrakin, Pitrakinra) |
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| Gene, Accession, CAS # | IL4, Gene ID: 16189, SwissProt: P07750 |
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| Catalog # | 219950 |
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| Order / More Info | IL-4, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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