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| Product Name | IL-6, Recombinant, Mouse |
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| Description | Purity ~98% (SDS-PAGE, HPLC). IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6Ra and gp130. Mouse IL-6 is inactive on human cells, while both human and murine are equally active on mouse cells. Source: Recombinant protein corresponding to 187aa residues from mouse IL-6, expressed in E. coli. Molecular Weight: ~21.7kD Biological Activity: The ED50, as determined by the dose-dependent stimulation of the proliferation of the IL-6 dependent mouse 7TD1 cells, is <0.02ng/ml, corresponding to a specific a |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL-6, Recombinant, Mouse (Interleukin 6, IL6, B Cell Stimulatory Factor 2, BSF-2, BSF2, CTL Differentiation Factor, CDF, HSF, Hybridoma Growth Factor, HGF, Interferon beta 2, IFN-beta-2, IFNB2) |
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| Gene, Accession, CAS # | IL6, Gene ID: 16193, SwissProt: P08505 |
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| Catalog # | 219958 |
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| Order / More Info | IL-6, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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