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| Product Name | IL4, Recombinant, Mouse |
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| Description | Purity ~95% (SDS-PAGE). IL-4 is produced mainly by a subpopulation of activated T cells (Th2) which are the biologically most active helper cells for B cells and which also secrete IL-5 and IL-6. Another subpopulation (Th1) also produces IL-4 albeit to a lesser extent. Non-T/Non-B cells of the lineage of mast cells also produce IL-4. The extracellular domain of the IL-4 receptor is related to the receptors for Epo, IL-6, and the beta chain of the IL-2 receptor. It has been given the name CD124. Two types of IL-4 receptor (IL-4R) exist: the type 1 receptor is a heterodimer consisting of CD132 and IL-4R-alpha. The type 2 receptor is a heterodimer consisting of IL-4R-alpha and IL-13R-alpha-1. The biological activities of IL-4 are species-specific; mouse IL-4 is inactive on human cells and human IL-4 is inactive on murine cells. IL-4 promotes the proliferation and differentiation of activated B cells, the expression of MHC class 2 antigens, and of low affinity IgE receptors in resting B-cells. IL-4 is probably an |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL4, Recombinant, Mouse (IL-4, B Cell IgG Differentiation Factor, B Cell Growth Factor 1, B Cell Stimulatory Factor 1, BSF-1, IGG1 Induction Factor, Lymphocyte Stimulatory Factor 1, Interleukin-4) |
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| Gene, Accession, CAS # | SwissProt: P07750 |
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| Catalog # | 500166 |
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| Order / More Info | IL4, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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