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| Product Name | IL5, Recombinant, Mouse |
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| Description | Purity ~95% (SDS-PAGE). Interleukin-5 is a specific hematopoietic growth factor that is responsible for the growth and differentiation of eosinophils. IL-5 promotes the growth of immature hematopoietic progenitor cells BFU-E while it causes differentiation of CFU-E the proliferation of which is inhibited by IL-5. IL-5 strongly stimulates the proliferation, cell activation, and differentiation of eosinophils. B cells can be made responsive to IL-5 by treatment with suboptimal doses of IL-1. Interleukin-5 also promotes the generation of cytotoxic T cells from thymocytes. In thymocytes IL-5 induces the expression of high affinity IL-2 receptors. In contrast to human Interleukin-5, mouse IL-5 also acts on B cells. It induces the proliferation of pre-activated B cells and their differentiation. High affinity and low affinity receptors for IL-5 are expressed in all hematopoietic and lymphoid cells.The low affinity receptor, CD125, has a molecular mass of 50kD (p60). The introduction of p60 into these cells generate |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL5, Recombinant, Mouse (IL-5, B-Cell Growth Factor II, BCGF-II, Cytotoxic T-Lymphocyte Inducer, Eosinophil Differentiation Factor, T-Cell Replacing Factor, TRF, Interleukin-5) |
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| Gene, Accession, CAS # | SwissProt: P04401 |
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| Catalog # | 500168 |
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| Order / More Info | IL5, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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