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| Product Name | KMO, Recombinant, Human, aa1-486, His-Tag (Kynurenine 3-monooxygenase) |
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| Description | Purity ~85% (SDS-PAGE). Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. Source: Recombinant protein corresponding to aa1-486 from human KMO, fused to His-Tag at N-terminal, expressed in Yeast. Molecular Weight: ~57.8kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Kynurenine 3-hydroxylase |
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| Gene, Accession, CAS # | SwissProt: O15229 |
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| Catalog # | 373943 |
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| Order / More Info | KMO, Recombinant, Human, aa1-486, His-Tag (Kynurenine 3-monooxygenase) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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