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| Product Name | Fc Receptor-like 5, Recombinant, Human (FCRL5, FcRH5) |
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| Description | Purity ≥95% (SDSPAGE). Fc Receptor-Like 5 (FCRL5), also known as FcRH5, IRTA2, and CD307, is a 120kD protein with sequence homology to classical Fc receptors. The type 1 transmembrane FCRL proteins contain from three to nine immunoglobulin-l i ke domains. They are differentially expressed within the B cell lineage and can either promote or inhibit B cell proliferation and activation. According to testing, FCRL5 binds to purified human IgG with high affinity. Mature human FCRL5 consists of a 836aa extracellular domain (ECD) with nine Ig-like domains, a 21aa transmembrane segment, and a 105aa cytoplasmic domain with one immunotyrosine activation motif (ITAM) and two immunotyrosine inhibitory motifs (ITIMs). Mouse FCRL5 contains only five Ig-like domains in its ECD. It shares 49% aa sequence identity with human FCRL5 within common regions. Alternate splicing of human FCRL5 generates isoforms that consist of approximately the first one, six, or eight Ig-like domains. FCRL5 expression is r |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: AAK93871 |
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| Catalog # | F0025-77 |
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| Order / More Info | Fc Receptor-like 5, Recombinant, Human (FCRL5, FcRH5) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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