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| Product Name | FCRLB, aa18-427, Recombinant, Mouse |
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| Description | Purity ~80% (SDS-PAGE). FCRLB, is a 60kD protein with sequence homology to classical Fc receptors. There are at least six type 1 transmembrane FCRL proteins and two that lack transmembrane segments. Each family member contains between three and nine immunoglobulin-like domains. FCRL proteins are differentially expressed within the B cell lineage and can either promote or inhibit B cell proliferation and activation (1, 2). According to R&D Systems testing, FCRLB binds to purified mouse IgG. Mouse FCRLB shares 82%, 94% aa sequence identity with human and rat FCRLB, respectively. It contains a putative signal peptide, three immunoglobulin-like domains, and a mucin-like stalk that is rich in Pro, Ser, and Thr residues (1-3). When expressed in transfectants, FCRLB is not secreted but shows a diffuse intracellular localization (4, 5). FCRLB is expressed at a low level in placenta and in B lineage cells of the germinal center (4, 5). It is up-regulated in B cells by BAFF and LPS (3). Among no |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | FCRLB, aa18-427, Recombinant, Mouse (FCRL2, FCRY, FREB2, Fc Receptor-like B, Fc Receptor-like and Mucin-like Protein 2, Fc Receptor-like Protein 2, Fc Receptor-related Protein Y) |
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| Gene, Accession, CAS # | SwissProt: Q5DRQ8 |
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| Catalog # | F0025-73A |
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| Order / More Info | FCRLB, aa18-427, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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