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| Product Name | FCRLB, Recombinant, Human |
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| Description | Purity ≥90% (SDS-PAGE). FCRLB, also known as FCRL2, FCRY, and FREB2, is a 60kD protein with sequence homology to classical Fc receptors. There are at least six type 1 transmembrane FCRL proteins and two that lack transmembrane segments. Each family member contains between three and nine immunoglobulin-like domains. FCRL proteins are differentially expressed within the B cell lineage and can either promote or inhibit B cell proliferation and activation. According to our testing, FCRLB binds to purified human IgG with high affinity. Human FCRLB shares 82% and 85% aa sequence identity with mouse and rat FCRLB, respectively. It contains a putative signal peptide, three immunoglobulin-like domains, and a mucin-like stalk that is rich in Pro, Ser, and Thr residues. The stalk region also contains di-Leu motifs and an unpaired cysteine. Alternative splicing generates isoforms with deletions in the putative signal peptide and substitutions and/or truncations in the third Ig -like domain. When e |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | FCRLB, Recombinant, Human (FCRL2, FCRY, FREB2, Fc Receptor-like B, Fc Receptor homolog expressed in B cells Protein 2, Fc Receptor-like and Mucin-like Protein 2, Fc Receptor-like Protein 2, Fc Receptor-related Protein Y, FCRLM2, FCRLY, FcRY, FLJ31052, FREB-2, RP11-474I16.6) |
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| Gene, Accession, CAS # | SwissProt: Q6BAA4 |
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| Catalog # | F0025-73 |
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| Order / More Info | FCRLB, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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