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| Product Name | FCRL5, Recombinant, Mouse |
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| Description | Purity ~95% (SDS-PAGE). Fc Receptor-Like 5 (FCRL5), also known as FcRH3 (FcRH5 in human), IRTA2, and CD307e, is a 90-95kD member of the FCRL family of proteins whose aa sequence is reminiscent of that for classical Fc receptors. FCLR molecules are type 1 transmembrane proteins that contain from three to nine immunoglobulin-like domains. They are differentially expressed within the B cell lineage, and can either promote or inhibit B cell proliferation and activation. Mature mouse FCRL5 consists of a 470aa extracellular domain (ECD), a 21aa transmembrane segment, and a 79aa cytoplasmic region. The ECD contains five Ig-like domains, while the cytoplasmic region possesses one ITAM-like motif and one immunotyrosine inhibitory motif (ITIM). There are two major alleles for FCLR5 in mouse. The first was just described, and is found in BALB/c plus NZB mouse strains. The second is found in C57BL/6 mice, and differs by eleven scattered aa in the ECD. This creates one additional N-linked glycosyla |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | FCRL5, Recombinant, Mouse (Fc Receptor-like Protein 5, FcR-like Protein 5, BXMAS1, Fc Receptor Homolog 5, FcRH5, Immune Receptor Translocation-associated Protein 2, CD307e, FCRH5, IRTA2, UNQ503/PRO820) |
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| Gene, Accession, CAS # | Accession: NP_899045 |
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| Catalog # | F0025-77C |
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| Order / More Info | FCRL5, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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