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| Product Name | TACI,Fc, Recombinant, Human |
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| Description | Purity >90% (SDS-PAGE). B-cell activating factor belonging to the TNF family receptor (BAFF-R), B-cell maturation antigen (BCMA), and transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) play critical functions in promoting B-cell survival by engaging the ligands a proliferation-inducing ligand (APRIL) and/or BAFF. TACI is predominantly expressed on peripheral blood B cells and interacts with the B cell activating factor (BAFF) of ligands and a proliferation inducing ligand (APRIL), which are expressed by numerous cell types, including dendritic cells, macrophages and neutrophils. TNFRSF13B, the gene, which encodes TACI is mutated in nearly 10% of patients with common variable immune deficiency (CVID), an antibody deficiency syndrome characterized by loss of memory B cells and plasma cells. Biological Activity: Inhibits BAFF and APRIL activity. Sequence: The extracellular domain of human TACI (aa 2-118) is fused at the C-terminus to the Fc portion of h |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TACI,Fc, Recombinant, Human (TNFRSF 13B, Tumor Necrosis Factor Receptor Superfamily Member 13B, Transmembrane Activator and CAML interactor, CD267) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 45324 |
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| Order / More Info | TACI,Fc, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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