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| Product Name | Vascular Endothelial Growth Factor B, Recombinant, Human |
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| Description | Purity ~98% (SDS-PAGE and HPLC). VEGF-B, a member of the VEGF family, is a potent growth and angiogenic cytokine. It promotes DNA synthesis in endothelial cells, helps regulate angiogenesis and vascular permeability, and inhibits apoptosis in certain smooth muscle cells and neurons. VEGF-B is expressed in all tissues except the liver. It forms cell surfaced-associated disulfide linked homodimers and can form heterodimers with VEGF-A. There are two known isoforms, formed by alternative splicing, which have been designated VEGF-B167 and VEGF-B186. Both forms have identical amino-terminal sequences encoding a ``cysteine knot'' like structural motif, but differ in their carboxyl-terminal domains. Both VEGF-B isoforms signal only through the VEGFR1 receptor. Recombinant human VEGF-B is a 38kD disulfide-linked homodimeric protein consisting of two 167aa polypeptide chains. Source: Recombinant protein corresponding to human VEGF-B, expressed in E. coli. Endotoxin: <0.1ng/ug (1EU/ug) AA Sequence |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Vascular Endothelial Growth Factor B, Recombinant, Human (VEGFB, VEGF-B, VEGF-related Factor, VRF, VEGFL) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 149582 |
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| Order / More Info | Vascular Endothelial Growth Factor B, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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