| 产品详情 |
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| Product Name | 10-DEBC hydrochloride |
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| Description | Purity ≥99% (HPLC). Selective inhibitor of Akt/PKB. Inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5uM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. Shows no activity at PDK1, SGK1 or PI 3-kinase. Inhibits cell growth (IC50 ~ 2-6uM) and induces apoptosis in rhabdomyosarcoma cells. Synonyms: 10-[4'-(N,N-Diethylamino)butyl]-2-chlorophenoxazine hydrochloride |
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| Size | 10mg, 50mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 10-[4'-(N,N-Diethylamino)butyl]-2-chlorophenoxazine hydrochloride |
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| Gene, Accession, CAS # | CAS: 925681-41-0 |
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| Catalog # | 254339 |
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| Order / More Info | 10-DEBC hydrochloride from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 产品资料 |
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