| 产品名称 |
FCAR, Recombinant, Human, aa22-227, His-Tag (Immunoglobulin alpha Fc Receptor, CD89, CTB-61M7.2, FcalphaRI) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | FCAR, Recombinant, Human, aa22-227, His-Tag (Immunoglobulin alpha Fc Receptor, CD89, CTB-61M7.2, FcalphaRI) |
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| Description | Purity ~85% (SDS-PAGE). FCAR, also known as immunoglobulin alpha Fc receptor isoform, is a member of the multichain immune recognition receptor family which is the most abundant immunoglobulin in mucosal areas but is only the second most common antibody isotype in serum. It plays a role in both pro- and anti-inflammatory responses depending on the state of IgA bound. It is also an important Fc receptor for neutrophil killing of tumor cells. When FCAR expressing neutrophils come into contact with IgA-opsonized tumor cells, the neutrophils not only perform antibody-dependent cell-mediated cytotoxicity, but also release the cytokines TNF-alpha and IL-1beta which cause increased neutrophil migration to the site. Source: Recombinant protein corresponding to aa22-227 from human FCAR, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~24.5kD (215aa) 28-40kD (SDS-PAGE under reducing conditions) Endotoxin: <1EU/1ug (determined by LAL method) AA |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_001991 |
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| Catalog # | 377804 |
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| Price | |
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| Order / More Info | FCAR, Recombinant, Human, aa22-227, His-Tag (Immunoglobulin alpha Fc Receptor, CD89, CTB-61M7.2, FcalphaRI) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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