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| Product Name | Tissue Factor (TF) Recombinant, Rabbit |
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| Description | Recombinant rabbit tissue factor is supplied as a ~46kD molecule. This apoprotein contains extra cellular and transmembrane domains of the tissue factor, plus an amino terminal leader sequence consisting of several domains which aid in expression and purification. Application: Human tissue factor has been cloned and expressed in both E. coli and Baculovirus expression systems and successfully configured into very sensitive thromboplastin reagents. However, these reagents have shown to be sensitive to Proteins Induced by Vitamin K Antagonism or Absence (PIVKAs) in patient clinical samples which can detrimentally affect laboratory test results. Thus a project was undertaken to clone and express rabbit tissue factor to overcome the PIVKA sensitivity and create a PT reagent raw material which builds upon the vast experience of using rabbit derived thromboplastins in the clinical laboratory setting. Using the published cDNA gene sequence for rabbit brain tissue factor, the gene was isolated |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P24055 |
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| Catalog # | 368519 |
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| Order / More Info | Tissue Factor (TF) Recombinant, Rabbit from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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