| 产品详情 |
| Edit |   |
|---|
| Product Name | Bacillus anthracis PA, Protective Antigen, Control Peptide (Anthrax) |
|---|
| Description | Anthrax infection is initiated by the inhalation, ingestion, or cutaneous contact with Bacillus anthracis endospores. B. anthracis produces three polypeptides that comprise the anthrax toxin: protective antigen (PA), lethal factor (LF), and edema factor (EF) (1,2 for review). PA binds to two related proteins on the cell surface; these are termed tumor epithelial marker 8 (TEM8)/anthrax toxin receptor (ATR) (3) and capillary morphogenesis protein 2 (CMG2) (4), although it is still unclear which is physiologically relevant. Following PA binding to its receptor, PA is cleaved into two fragments by a furin-like protease. The bound fragment binds both LF and EF; the resulting complex is then endocytosed which allows the translocation of LF and EF into the cytoplasm (5). These toxins are usually sufficient to cause rapid cell death, and often the death of the organism. Location: 14aa near the carboxy-terminus of Anthrax protective antigen (1). Applications: The peptide is used for blocking t |
|---|
| Size | 50ug |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA WB |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | B0003-05N3 |
|---|
| Price | |
|---|
| Order / More Info | Bacillus anthracis PA, Protective Antigen, Control Peptide (Anthrax) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|