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| Product Name | AITRL, Recombinant, Human (Activation-induced TNFR member Ligand, TNFSF18, GITRL, TL-6) |
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| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. AITRL, a member of the TNF superfamily, is expressed in endothelial cells, and signals through the AITR receptor. AITRL regulates T-cell proliferation and survival, and effectuates the interaction between T lymphocytes and endothelial cells.The AITRL gene codes for a type II transmembrane protein comprised of 177aa, including a 28aa cytoplasmic region, a 21aa transmembrane domain and a 128aa extracellular domain.Recombinant human soluble AITRL is a 14.4kD protein, containing 127aa residues corresponding to the extracellular domain of AITRL. Biological Activity: Determined by its ability to stimulate IL-8 production by human PBMC using a concentration range of 1-10ng/ml. Note: Results may vary with PBMC donors. AA Sequence: METAKEPCMAKFGPLPSKWQMASSEPPCVNKVSDWKLEILQNGLYLIYGQVAPNANYNDVAPFEVRLYKNKDMIQTLTNKSKIQNVGGTYELHVGDTIDLIFNSEHQVLKNNTYWGIILLANPQFI Quality Control: Verified by N-terminal and Mass Spectrometry analyses (when applicable). End |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143272 |
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| Order / More Info | AITRL, Recombinant, Human (Activation-induced TNFR member Ligand, TNFSF18, GITRL, TL-6) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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