| 产品名称 |
IDO1, Recombinant, Human, aa1-403, His-Tag (Indoleamine 2,3-Dioxygenase, IDO, IDO-1, INDO) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | IDO1, Recombinant, Human, aa1-403, His-Tag (Indoleamine 2,3-Dioxygenase, IDO, IDO-1, INDO) |
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| Description | Purity ~90% (SDS-PAGE). IDO1 is an indoleamine 2,3-dioxygenase - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, and serotonin. It is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its pericellular catabolization of the essential amino acid tryptophan. Source: Recombinant protein corresponding to aa1-403 from human IDO1, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~47.7 kD (426aa), confirmed by MALDI-TOF Endotoxin: 300pmol/min/ug, and is defined as the amount of enzyme that hydrolyze 1pmole of L-Tryptophan to N-formyl-L- kynurenine/minu |
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| Size | 20ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_002155, SwissProt: P14902 |
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| Catalog # | 377842 |
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| Order / More Info | IDO1, Recombinant, Human, aa1-403, His-Tag (Indoleamine 2,3-Dioxygenase, IDO, IDO-1, INDO) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 产品资料 |
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