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| Product Name | Interleukin-1 beta, Recombinant, Mouse (IL-1 beta) |
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| Description | Purity ~98% (SDS-PAGE, HPLC). Interleukin-1 beta (IL-1 beta), is an ~17.5kD proinflammatory, cell-associated cytokine, produced by monocytes, tissue macrophages, keratinocytes and other epithelial cells. IL-1 beta promotes the proliferation of memory T cells and cytokine production. It attenuates regulatory T cell function and enables CD4+CD25- autoreactive effectors to avoid suppression. IL-1 beta signals downstream of myc and is required for angiogenesis and invasiveness of tumour cells. IL-1 beta is directly involved in neuronal injury in neurodegenerative disorders, and stimulates mitogenic FGF-like activity, bone resorption and promotes the release of collagenase and prostaglandin from synovial cells. Source: Recombinant protein corresponding to mouse Interleukin-1 beta expressed in E. coli. Molecular Weight: ~17.5kD (153aa) Biological Activity: The ED50 as determined by the dose-dependent stimulation of murine D10S cells is 5x |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 214926 |
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| Order / More Info | Interleukin-1 beta, Recombinant, Mouse (IL-1 beta) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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