| 产品详情 |
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| Product Name | KU 0060648 |
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| Description | Highly Purified (~97%). Dual PI 3-K and DNA-PK inhibitor (IC50 values are <0.1, 0.5, 4 and 19 nM for PI 3-Kdelta, PI 3-Kbeta, PI 3-Kalpha and DNA-PK respectively). Inhibits proliferation of MCF7 cells in vitro and delays growth of MCF7 xenografts in mice. Also enhances CRISPR-Cas9-mediated homology- directed repair (HDR) efficiency, and attenuates nonhomologous end-joining (NHEJ). Formula: C33H34N4O4S Solubility: Soluble to 100mM in 2eq.HCl Molecular Weight: 582.71 |
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| Size | 10mg, 50mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-Ethyl-N-[4-[2-(4-morpholinyl)-4-o xo-4H-1-benzopyran-8-yl]-1-dibenzothienyl]-1-piper azineacetamide |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 255613 |
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| Order / More Info | KU 0060648 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 产品资料 |
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