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| Product Name | LSD1, Homogeneous, BioAssay™ Kit (Lysine-Specific Histone Demethylase, KDM1A, AOF2, BHC110) |
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| Description | LSD1 is a chromatin-modifying enzyme that specifically removes methyl groups from mono- and dimethylated Lys of histone H3. LSD1 is a critical component of transcriptional regulation via epigenetic histone modifications and is therefore a potential target for drug development. Intended Use: The LSD1 Homogeneous BioAssay™ Kit is designed to measure activity of lysine-specific demethylase (LSD1) for screening and profiling applications. Test Principle: The key to the LSD1 Homogeneous BioAssay™ Kit is a highly specific antibody that recognizes demethylated substrate. With this kit, only three simple steps on a microtiter plate are required for demethylase detection. First, a sample containing LSD1 enzyme is incubated with the biotinylated substrate. Next, acceptor beads and primary antibody are added, then donor beads, followed by reading the Alpha-counts. Applications: Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS appli |
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| Size | 1 kit |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: O60341 |
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| Catalog # | 298429 |
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| Order / More Info | LSD1, Homogeneous, BioAssay™ Kit (Lysine-Specific Histone Demethylase, KDM1A, AOF2, BHC110) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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