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| Product Name | MG-132, Z-Leu-Leu-Leu-CHO (Carbobenzoxy-L-leucyl-L-leucyl-L-leucinal, Proteasome Inhibitor XI) |
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| Description | Purity ~95% (HPLC). Potent, reversible, and cell-permeable proteasome inhibitor (Ki=4nM). Reduces the degradation of ubiquitin-conjugated proteins in mammalian cells and permeable stains of yeast by the 26S complex without affecting its ATPase or isopeptidase activities. Activates c-Jun N-terminal kinase (JNK1) which initiates apoptosis. Inhibits NF-kB activation (IC50=3uM). This material is ≥95% pure by HPLC. Formula: C26H41N3O5 Solubility: DMSO or EtOH Molecular Weight: 475.6 |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217547 |
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| Order / More Info | MG-132, Z-Leu-Leu-Leu-CHO (Carbobenzoxy-L-leucyl-L-leucyl-L-leucinal, Proteasome Inhibitor XI) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 产品资料 |
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