| 产品详情 |
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| Product Name | Relaxin 2 |
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| Description | Purity ~97% (SDS-PAGE). Human Relaxin-2, also called H2 Relaxin, is a 6kD, 53aa nonglycosylated, heterodimeric polypeptide that plays an important role in female reproduction (1, 2). Relaxin belongs to a structurally related insulin/relaxin superfamily that currently contains 10 members in human (2). To date, three human relaxin genes have been identified (1, 2). Among these, Relaxin-2 is best studied and the only known Relaxin to circulate in the blood (2, 3). As with other insulin/relaxin superfamily members, human Relaxin-2 is synthesized as a preprohormone (4). It is 18kD in size and 185 aa in length. It contains a 24 aa signal sequence, a 3.3kD, 31 aa B domain, a 106 aa C (or connecting) domain, and a C-terminal, 2.7kD, 24 aa A domain (2, 4, 5). Upon removal of the signal peptide, two intrachain disulfide bonds are created between the B and A chains. This is followed by prohormone convertase removal of the intervening C-chain, creating a disulfide-linked heterodimer. Initially, th |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Relaxin 2 (B-29/A-24), Recombinant, Human (RLN2, bA12D24.1.1, bA12D24.1.2, H2, Prorelaxin H2, RLXH2) |
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| Gene, Accession, CAS # | SwissProt: P04090 |
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| Catalog # | R1425-02L |
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| Order / More Info | Relaxin 2 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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