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HPD, Recombinant, Mouse, aa1-393, His-Tag (4-Hydroxyphenylpyruvate Dioxygenase, 4HPPD, Fla, Flp, Hppd, Laf) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | HPD, Recombinant, Mouse, aa1-393, His-Tag (4-Hydroxyphenylpyruvate Dioxygenase, 4HPPD, Fla, Flp, Hppd, Laf) |
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| Description | Purity ~90% (SDS-PAGE). Hpd, also known as 4-hydroxyphenylpyruvate dioxygenase, is a Fe-containing enzyme that catalyzes the second reaction in the catabolism of tyrosine the conversion of 4-hydroxyphenylpyruvate to homogentisate. Existing as a homodimer, Hpd uses zinc as a cofactor to catalyze the third step in the conversion of L- phenylalanine to fumarate and acetoacetic acid. Defects in the gene encoding Hpd are the cause of tyrosinemia type 3 and hawkinsinuria, both of which are inborn errors of metabolism that are associated with a variety of symptoms, including mental retardation and seizures and hair and urine abnormalities. Source: Recombinant protein corresponding to aa1-393 from mouse Hpd, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~47.4kD (416aa) (confirmed by MALDI-TOF) Enzyme Activity: Not determined. This product is recommended for use in applications that do not require a catalytically active form of the protein. AA |
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| Size | 10ug, 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_032303 |
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| Catalog # | 470236 |
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| Order / More Info | HPD, Recombinant, Mouse, aa1-393, His-Tag (4-Hydroxyphenylpyruvate Dioxygenase, 4HPPD, Fla, Flp, Hppd, Laf) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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