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| Product Name | Hp, Recombinant, Rat, aa19-346, His-Tag (Haptoglobin) |
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| Description | Purity ~90% (SDS-PAGE). As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of he iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens. Source: Recombinant protein corresponding to aa19-346 from rat Haptoglobin, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~40.6kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Liver regeneration-related protein LRRG173Zonulin |
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| Gene, Accession, CAS # | SwissProt: P06866 |
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| Catalog # | 373676 |
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| Order / More Info | Hp, Recombinant, Rat, aa19-346, His-Tag (Haptoglobin) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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