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| Product Name | Osteopontin (OPN), BioAssay™ ELISA Kit (Human) |
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| Description | Human Osteopontin (OPN) ELISA BioAssay™ Kit is an in vitro assay for the quantitative measurement of human OPN. OPN is a multifunctional, hyperphosphorylated acidic glycoprotein. As a key component of extracellular matrix-associated protein abundantly expressed in bone, OPN is a key regulator of bone mineralization. In addition, OPN is expressed in multiple other cell types including macrophages, smooth muscle cells and hepatocytes. OPN up-regulation occurs upon exposure to pro-inflammatory cytokines (TNF-alpha, TGF-beta etc.) or under pathological conditions such as hypoxia and hyperglycemia. OPN also functions as a chemokine-like protein involved in regulating cell proliferation, inflammatory responses, angiogenesis and metastasis, and is critical in the development of multiple disorders including cardiovascular disease, diabetes, and cancer. Sample Type: Plasma, serum, and cell culture supernatants Intended Use: Quantitative measurement of native and recombinant human Osteopontin (O |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | BNSP, BSPI, ETA-1, MGC110940, OPN, SPP1/CALPHA1 fusion|bone sialoprotein I|early T-lymphocyte activation 1|osteopontin|osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 301259 |
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| Order / More Info | Osteopontin (OPN), BioAssay™ ELISA Kit (Human) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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