| 产品详情 |
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| Product Name | SIRP, alpha1, aa487-503, Blocking Peptide |
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| Description | Control peptide for S1013-87. Protein tyrosine phosphatases (PTPases) SHP-1 and SHP-2 are critical regulators in the intracellular signaling pathways that result in cell responses such as mitosis, differentiation, migration, survival, transformation or death. SHP-2 is a signal transducer for several receptor tyrosine kinases and cytokine receptors. A novel SHP-2 associated glycoprotein was recently cloned from human, rat, mouse and cattle by several labs and was designated SIRPa, SHPS-1, MyD-1, BIT and p84. SIRPa is a new gene family containing at least fifteen members. SIRPa is a substrate of many activated tyrosine kinases such as insulin receptor, EGFR, PDGFR and src, and a specific docking protein for SHP-2. SIRPa has regulatory effects on cellular responses induced by serum, growth factors, insulin, oncogenes, growth hormones and cell adhesion. It plays a general role in different physiological and pathological processes. Applications: Sutiable for use in Antibody Blocking. |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | SIRP, alpha1, aa487-503, Blocking Peptide (SIRPa, Signal Regulatory Protein, SHPS-1, BIT, p84, CD172a) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | S1013-87A |
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| Price | |
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| Order / More Info | SIRP, alpha1, aa487-503, Blocking Peptide from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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