| 产品名称 |
Glycerol Kinase, Recombinant, E. coli, aa1-502 (GK, GK1, GKD, glpK, Glycerokinase) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | Glycerol Kinase, Recombinant, E. coli, aa1-502 (GK, GK1, GKD, glpK, Glycerokinase) |
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| Description | Purity ~75% (SDS-PAGE). Glycerol kinase from E. coli (glpK) catalyzes the ATP-dependent phosphorylation of glycerol to produce sn-glycerol-3-phosphate (G3P), the first and ratelimiting step in the utilization of glycerol (1). In the presence of glycerol, glpK is stimulated by interaction with the membrane-bound glycerol facilitator (2). In the presence of glucose, glpK activity is allosterically inhibited by fructose-1,6bisphosphate (FBP) of the glycolytic pathway (3). Under physiological conditions, the enzyme is in an equilibrium between the active dimer and the inactive tetramer. FBP binds to and stabilizes the inactive form, therefore shifting the usage of glycerol metabolic pathway to glycolytic pathway (4). glpK is also inhibited by phosphocarrier protein IIAGlc by a regulatory mechanism distinct from that of FBP (5). GlpK is a member of a superfamily of ATPases that includes actin, hexokinase and the heat shock protein hsc70. Although these proteins are dissimilar in amino aci |
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| Size | 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 145796 |
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| Order / More Info | Glycerol Kinase, Recombinant, E. coli, aa1-502 (GK, GK1, GKD, glpK, Glycerokinase) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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