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| Product Name | FBXO3, Recombinant, Human, aa1-471, His-Tag (F-box Only Protein 3) |
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| Description | Purity ~90% (SDS-PAGE). Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation. Source: Recombinant protein corresponding to aa1-471 from human FBXO3, fused to His-Tag at N-terminal, expressed in Yeast. Molecular Weight: ~56.6kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q9UK99 |
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| Catalog # | 373291 |
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| Order / More Info | FBXO3, Recombinant, Human, aa1-471, His-Tag (F-box Only Protein 3) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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