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| Product Name | PEDF/SerpinF1, BioAssay™ ELISA Kit (Human) (Pigment Epithelium Derived Factor) |
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| Description | Pigment epithelium-derived factor (PEDF) is also known as serpin F1 (SERPINF1). In humans, it is encoded by the SERPINF1 gene. PEDF has a variety of functions including antiangiogenic, antitumorigenic, and neurotrophic properties. It suppresses retinal neovascularization and endothelial cell proliferation. And Antiangiogenic function is also conferred by PEDF through inhibition of both VEGFR-1 and VEGFR-2. In addition, the antitumorigenic effects of PEDF are not only due to inhibition of supporting vasculature, but also due to effects on the cancer cells themselves. PEDF is shown to inhibit cancer cell proliferation and increase apoptosis via the FAS/FASL pathway. Expression of PEDF in the human retina is found at 7.4 weeks of gestation, suggesting it may play a role in retinal neuron differentiation. Sample Type: Cell culture supernates, serum and plasma (heparin, EDTA) Intended Use: For quantitative detection of human PEDF in cell culture supernates, serum and plasma (heparin, EDTA). |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gene ID: 5176, SwissProt: P36955 |
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| Catalog # | 353000 |
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| Order / More Info | PEDF/SerpinF1, BioAssay™ ELISA Kit (Human) (Pigment Epithelium Derived Factor) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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