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| Product Name | DCTN2, Recombinant, Human, aa1-406, His-Tag (Dynactin Subunit 2 Isoform 1) |
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| Description | Purity ~90% (SDS-PAGE). DCTN2 is a 50kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22-150kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Source: Recombinant corresponding to aa1-406 from human DCTN2 protein, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~47.2kD (429aa), confirmed by MALDI-TOF Applications: Suitable for use in SDS-PAGE. |
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| Size | 100ug, 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_006391 |
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| Catalog # | 218096 |
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| Order / More Info | DCTN2, Recombinant, Human, aa1-406, His-Tag (Dynactin Subunit 2 Isoform 1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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