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| Product Name | Rage BioAssay™ ELISA Kit, Human |
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| Description | Sandwich ELISA quantitative detection kit for Human Rage in cell culture supernates, serum and plasma (heparin, EDTA). RAGE, the Receptor for Advanced Glycation Endproducts, is a 35kD transmembrane receptor of the immunoglobulin super family. It is also known as ``AGER''. AGER gene is mapped to chromosome 6p21.3 by mapping by contiguous cosmids and YAC clones and by fluorescence in situ hybridization. The expression of RAGE is particularly increased in neurons close to deposits of amyloid beta peptide and to neurofibrillary tangles. RAGE has been linked to several chronic diseases, which are thought to result from vascular damage. The pathogenesis is hypothesized to include ligand binding upon which RAGE signals activation of the nuclear factor kappa B (NF-κB). Assay Range: 78pg/ml-5000pg/ml Sensitivity: < 10 pg/ml Crossreactivity: There is no detectable cross-reactivity with other relevant proteins. Uniprot ID: B4DNX3 Entrez Gene ID: 177 Kit Components: 96-well plate pre-coated wi |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gene ID: 177, SwissProt: B4DNX3 |
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| Catalog # | 144019 |
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| Order / More Info | Rage BioAssay™ ELISA Kit, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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