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| Product Name | PPP1R14A, Recombinant, Human |
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| Description | Purity ≥ 90% by SDS-PAGE. Purified using conventional chromatography techniques. PPP1R14A (Protein phosphatase 1 regulatory subunit 14A) is a phosphorylation-dependent inhibitory protein for smooth muscle myosin phosphate. Myosin phosphatase can reverse MYL (myosin light chain) phosphorylation to induce a state of relaxation. However, during agonist-induced contraction at constant Ca2+ concurrent inhibition of myosin phosphatase leads to increases in MYL phosphorylation and tension. These calcium-independent increases in myosin phosphorylation and tension are termed calcium sensitization. Recombinant protein corresponding to aa1-167 of human PPP1R14A fused to a His-tag at the N-terminal expressed in E. coli (NP_150281). Sequences: MGSSHHHHHH SSGLVPRGSH MAAQRLGKRV LSKLQSPSRA RGPGGSPGGL QKRHARVTVK YDRRELQRRL DVEKWIDGRL EELYRGMEAD MPDEINIDEL LELESEEERS RKIQGLLKSC GKPVEDFIQE LLAKLQGLHR QPGLRQPSPS HDGSLSPLQD RARTAHP Enzyme Activity: Not determined. This product is recommended for use in app |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PPP1R14A, Recombinant, Human (Protein phosphatase 1 regulatory subunit 14A, CPI17, CPI-17, PPP1INL) |
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| Gene, Accession, CAS # | Accession: NP_150281 |
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| Catalog # | P9107-30Z |
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| Order / More Info | PPP1R14A, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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