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| Product Name | NOS I, Human (Nitric Oxide Synthase 1, bNOSn, NOS-1) (Control Peptide) |
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| Description | Highly purified. Rat brain NOS control peptide. Corresponding antibody recognizes ~150-160kD Human NOS I. Sequence is conserved in mouse, 85%, human, 84% and rabbit, 68%. No significant sequence homology is seen with NOS-2/NOS-3. Nitric oxide (NO), a diffusible free radical gas, acts as a neurotransmitter in brain and peripheral nervous system. It accounts for the activity of endothelium-derived relaxing factors, which stimulate vasodilatation by releasing NO from the endothelium. Unlike typical neurotransmitter, NO is a not stored in synaptic vesicle and does not act on membrane receptors. Synthesis of NO, initially demonstrated in vascular endothelium, is now found in many tissues. NO is synthesized by L-arginine, oxygen, and NADPH by three known isoforms of heme-containing flavoproteins termed NO synthase (NOS, I-III, ~130-160kD). One group of enzyme is constitutive, agonist-triggered, and dependent on Ca2+/Calmodulin and is inhibited by L-arginine analogues (L-NNA, L-NMMA). It is f |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | N5350-05 |
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| Order / More Info | NOS I, Human (Nitric Oxide Synthase 1, bNOSn, NOS-1) (Control Peptide) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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