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| Product Name | TGFBR2, BioAssay™ ELISA Kit (Human) (Transforming Growth Factor Beta Receptor II) |
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| Description | TGFBR2(transforming growth factor, beta receptor II (70/80kD)), also known as TGF-beta receptor type-2, TGFR-2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II( TGF-beta receptor type II, TbetaR-II), is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. A TGFBR2 cDNA encoding a deduced 565aa protein with a calculated molecular mass of approximately 60 kD in length. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler-Weber-Rendu syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different informs |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gene ID: 7048, SwissProt: P37173 |
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| Catalog # | 353065 |
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| Order / More Info | TGFBR2, BioAssay™ ELISA Kit (Human) (Transforming Growth Factor Beta Receptor II) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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