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| Product Name | LYN A, Recombinant, Human, GST-Tag (Tyrosine-protein Kinase Lyn, JTK8, FLJ26625) |
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| Description | Purified (~70-90%). LYN A is a member of the Src-family of protein kinases that participate in signaling pathways of a variety of cell surface receptors and are localized to the cytoplasmic side of the plasma membrane. LYN A is biosynthetically transported to the plasma membrane via the Golgi pool of caveolin along the secretory pathway. The trafficking of LYN A from the Golgi apparatus to the plasma membrane is inhibited by deletion of the kinase domain but not by kinase inactivation. The kinase domain of LYN A plays a role in LYN A trafficking besides catalysis of substrate phosphorylation. cDNA microarray analysis revealed that LYN A may be involved in the changes that are related to tumor pathogenesis. Source: Recombinant protein corresponding to human LYN A, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~81kD Specific Activity: 571nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_002350 |
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| Catalog # | 500221 |
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| Order / More Info | LYN A, Recombinant, Human, GST-Tag (Tyrosine-protein Kinase Lyn, JTK8, FLJ26625) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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