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| Product Name | PDGFB, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). The PDGF family is comprised of five different disulphide-linked dimers of four different polypeptide chains: A, B, C and D (PDGF-AA, PDGF-BB, PDGF-AB, PDGF-CC and PDGF-DD). Synthesized mainly by megakaryocytes, PDGFs are stored in the alpha granules of platelets from which they are released following platelet activation. Functioning as an autocrine and paracrine growth factor, PDGFs are involved in a number of biological processes that include but not limited to hyperplasia, chemotaxis, embryonic neuron development, wound healing and respiratory tubule epithelial cell development. Aberrant expression of PDGFs is observed with vascular proliferative diseases such as atherosclerosis. PDGFs regulate the synthesis of their own receptor and also influence the expression of membrane receptors for IL1, EGF, 5-Hydroxytryptamine, LDL and transferrin. Recombinant human PDGFB is a disulfide-linked homodimer of two B chains. Source: Recombinant protein corresponding to human PDGFB expressed in E. |
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| Size | 10ug, 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PDGFB, Recombinant, Human (PDGF Subunit B, PDGF-2, Platelet-Derived Growth factor B Chain, Platelet-Derived Growth Factor Beta Polypeptide, Proto-Oncogene c-Sis, PDGF-BB, Platelet-Derived Growth Factor Subunit B) |
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| Gene, Accession, CAS # | SwissProt: P01127 |
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| Catalog # | 500346 |
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| Order / More Info | PDGFB, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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