| 产品详情 |
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| Antigenic Specificity | CCL5 / RANTES |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | ELISA (0.5 - 2 µg/ml), Func (5 - 7 µg/ml), WB (0.1 - 0.2 µg/ml) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CCL5 / RANTES Antibody LS-C42727. Recognizes human RANTES (regulated upon activation, normal T cell expressed and secreted), otherwise known as CCL5, a 68 amino acid CC- chemokine involved in T cell activation and cell recruitment, expressed by cytotoxic (CD8+) T cells (CTLs), macrophages, keratinocytes and endothelial cells. RANTES acts as a chemoattractant for monocytes, CD4+/CD45RO+ memory T cells, basophils and eosinophils, thorough binding to chemokine (C-C motif) receptor 1 (CCR1), CCR3 and CCR5. Both CCR3 and CCR5 are known co-receptors for the entry of HIV viruses into target cells and the binding of RANTES to CCR3 on CTLs has been shown to enhance HIV-1-specific cytotoxicity, whilst binding to CCR5 inhibits membrane fusion and hence HIV entry. |
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| Immunogen | Recombinant human RANTES. |
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| Other Names | CCL5, Chemokine (C-C motif) ligand 5, D17S136E, EoCP, T-cell specific protein p288, SCYA5, SISd, T cell-specific protein P228, Beta-chemokine RANTES, C-C motif chemokine 5, RANTES, SIS-delta, Small-inducible cytokine A5, T-cell-specific protein RANTES, TCP228 |
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| Gene, Accession # | CCL5, Gene ID: 6352 |
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| Catalog # | LS-C42727 |
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| Price | |
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| Order / More Info | CCL5 / RANTES Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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