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| Product Name | IGFBP4, BioAssay™ ELISA Kit (Human) (Insulin Like Growth Factor Binding Protein 4) |
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| Description | Insulin-like growth factor-binding protein 4 is a protein that in humans is encoded by the IGFBP4gene. This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. In addition, IGFBP-4 is a unique protein and it consistently inhibits several cancer cells in vivo and in vitro. Its inhibitory action has been shown in vivo in prostate and colon. It is secreted by all colon cancer cells. Sample Type: Cell culture supernates, serum and plasma (heparin, EDTA) Intended Use: For quantitative detection of human IGFBP4 in cell culture supernates, serum, and plasma (heparin, EDTA). Sensitivity: <20pg/ml Range: 500-32000pg/ml Specificity: |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gene ID: 3487, SwissProt: P22692 |
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| Catalog # | 352918 |
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| Order / More Info | IGFBP4, BioAssay™ ELISA Kit (Human) (Insulin Like Growth Factor Binding Protein 4) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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