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| Product Name | Cathepsin S (CTSS) Inhibitor Screening BioAssay™ Kit (Fluorometric) |
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| Description | Cathepsin S (CTSS, EC 3.4.22.27) is a lysosomal cysteine proteinase that is suggested to participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. Intended Use: To screen, study and characterize potential inhibitors of Cathepsin S. Test Principle: The Cathepsin S Inhibitor Screening BioAssay™ Kit utilizes the ability of Cathepsin S to cleave the synthetic AFC based peptide substrate to release AFC, which can be easily quantified using a fluorometer or fluorescence microplate reader. In the presence of a Cathepsin S inhibitor, the cleavage of the substrate is reduced/abolished resulting in decrease or total loss of the AFC fluorescence. This high-throughput adaptable assay kit is simple, sensitive, and rapid tool to screen the potential inhibitors of Cathepsin S. Kit Components: CTSS Reaction Buffer, 1x15ml?Cathepsin S (human), 1x vial?CTSS Substrate, Z-VVR-AFC, 10mM, 1x0.2ml?CTSS Inhibitor, Z-FF-FMK, 1mM, 1x20ul |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 219615 |
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| Order / More Info | Cathepsin S (CTSS) Inhibitor Screening BioAssay™ Kit (Fluorometric) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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