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| Product Name | Nociceptin, Control Peptide (Orphanin FQ, OFQ) |
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| Description | Serum. Control Peptide for N2982-10, N2982-12. Orphanin FQ (nociceptin, OFQ), a heptadecapeptide peptide, has been designated as an endogenous ligand for the ORL1 receptor. The amino acid sequence of OFQ has homology with other opioid peptides, especially the prodynorphin fragment dynorphin A, suggesting a close evolutionary relationship between the precursors. A diffuse distribution throughout the brain is seen with binding studies and in situ hybridization suggesting an extensive role for OFQ in a multitude of CNS functions. Immunocytochemical localizations in rat spinal cord have demonstrated OFQ abundance in superficial dorsal horn, lateral spinal nucleus and the region dorsal to the central canal. OFQ immunoreactivity was not affected by dorsal rhizotomy, indicating that in spinal cord the peptide is produced by central rather than primary afferent neurons. The localization is supported by its function in processing of nociceptive signals. Source: Synthetic peptide corresponding t |
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| Size | 50ul |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 299477 |
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| Order / More Info | Nociceptin, Control Peptide (Orphanin FQ, OFQ) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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