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| Product Name | Activating Transcription Factor 3 , Recombinant, Human, aa1-181 |
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| Description | Purity ~90% (SDS-PAGE). ATF3 (activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription, it is presumed, by sequestering inhibitory co-factors away from the promoter. Recombinant protein corresponding to aa1-181 of human ATF3, expressed in E. coli (NP_001665). Amino Acid Sequence: MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRN |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Activating Transcription Factor 3 , Recombinant, Human, aa1-181 (ATF3, cAMP-dependent Transcription Factor ATF-3, Cyclic AMP-dependent Transcription Factor ATF-3) |
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| Gene, Accession, CAS # | Accession: NP_001665 |
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| Catalog # | A0855-58J |
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| Order / More Info | Activating Transcription Factor 3 , Recombinant, Human, aa1-181 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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