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| Product Name | Activation-induced Cytidine Deaminase (AICDA, AID, ARP2, CDA2, HIGM2) (Control Peptide) |
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| Description | Highly Purified. Synthetic peptide corresponding to 14 amino acids near the carboxy-terminus of human AID (GenBank accession no. AAM95402). See corresponding antibody A0855-75J. Activation-induced cytidine deaminase (AID) was initially discovered as a homolog of the apolipoprotein B RNAediting cytidine deaminase 1 (APOBEC1) that showed cytidine deaminase properties in stimulated B cell lines (1). It is necessary for somatic hypermutation and class switch recombination in B cells (2), but inappropriate or dysregulated expression AID is often found in tumors and B cell neoplasms (2,3). Although it is structurally and functionally similar to the APOBEC proteins (reviewed in 4), it appears unlikely that AID deaminates dC to dU residues in HIV cDNA as does APOBEC3G (5). Applications: Suitable for use as a blocking peptide in ELISA, Western Blot with A0855-75J. |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | EC=3.5.4.5 |
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| Gene, Accession, CAS # | Accession: AAM95402 |
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| Catalog # | A0855-75J1 |
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| Order / More Info | Activation-induced Cytidine Deaminase (AICDA, AID, ARP2, CDA2, HIGM2) (Control Peptide) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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