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Bgn, Recombinant, Mouse, aa38-369, hIgG-His-Tag (Biglycan Preproprotein, Bgn, BG, DSPG1, PG-S1, PGI, SLRR1A) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | Bgn, Recombinant, Mouse, aa38-369, hIgG-His-Tag (Biglycan Preproprotein, Bgn, BG, DSPG1, PG-S1, PGI, SLRR1A) |
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| Description | Purity ~90% (SDS-PAGE). Bgn, also known as biglycan preproprotein, is a small leucine-rich repeat proteoglycan (SLRP). It binds to the growth factors BMP-4 and influences BMP-4 bioactivity. It plays an important role in stabilizing fibrotic scars after experimental myocardial infarction. It may function in connective tissue metabolism by binding to collagen fibrils and TGF-beta and may promote neuronal survival. Its ablation improves cardiac function and attenuates left ventricular hypertrophy and fibrosis after long-term pressure overload. It is found in a variety of extracellular matrix tissues, including bone, cartilage and tendon. Recombinant mouse Bgn, fused to hIgG-His-Tag at C-terminal, expressed in insect cell and purified by using conventional chromatography techniques. Source: Recombinant protein corresponding to aa38-369 of mouse Bgn, fused to hIgG-His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~64.6kD (574aa), ~50-70kD (SDS-PAGE under reducing conditions) Endotoxin: <1EU/1ug (d |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_031568 |
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| Catalog # | 396834 |
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| Order / More Info | Bgn, Recombinant, Mouse, aa38-369, hIgG-His-Tag (Biglycan Preproprotein, Bgn, BG, DSPG1, PG-S1, PGI, SLRR1A) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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