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| Product Name | BRAF, Recombinant, Human, GST-tag |
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| Description | Purified (~70-90%). BRAF is a member of the RAF family that is activated by members of the Ras family upon growth factor-induced stimulation. Active Ras can induce heterodimerization of cRaf and BRAF and this may explain the observed cooperativity of cRaf and BRAF in cells responding to growth factor signals. Activating mutations in the BRAF gene are present in a large percentage of human malignant melanomas and in a proportion of colon cancers. The vast majority of these mutations result in a valine to glutamic acid change at residue 599 within the activation segment of BRAF. Source: Recombinant protein corresponding to human BRAF, fused at GST-Tag at N-terminal, expressed in Insect cells. Molecular Weight: ~69kD Specific Activity: 2300nmol/min/mg in a coupled assay as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | BRAF, Recombinant, Human, GST-Tag (Serine/Threonine-protein Kinase B-raf, BRAF1, RAFB1, B-raf, B-raf 1, MGC126806, MGC138284) |
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| Gene, Accession, CAS # | Accession: NM_004333 |
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| Catalog # | 499824 |
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| Order / More Info | BRAF, Recombinant, Human, GST-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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