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| Product Name | Platelet Derived Growth Factor AA, Recombinant, Human (PDGF-AA) |
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| Description | Purity ~97% (RP-HPLC, SDS-PAGE). PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGF is stored in platelet alpha-granules and released upon platelet activation. The PDGF is involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGF have been identified and named PDGFR-alpha and PDGFR-beta. PDGFR-alpha is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-beta interacts with only PDGF-BB and PDGF-AB. Source: Recombinant protein corresponding to human PDGF-AA, a homodimeric, non-glycosylated, polypeptide chain containing 2x125aa, expressed in E. coli. Molecular Weight: ~28.51kD Biological Activity: The ED50, calculated by the dose-dependant proliferation of murine BALB/c 3T |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 299509 |
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| Order / More Info | Platelet Derived Growth Factor AA, Recombinant, Human (PDGF-AA) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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