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| Product Name | Antithrombin (ATIII) BioAssay™ ELISA Kit (Antibodies only) |
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| Description | Matched-Pair Antibody Set for ELISA of human Antithrombin antigen (ATIII). Sufficient reagents to perform 5 x 96 well plates. Antithrombin, also known as Antithrombin III (ATIII), is a member of the SERPIN family of proteinase inhibitors. It is the primary inhibitor of thrombin in plasma. It is produced in the liver and circulates in plasma at ~200ug/ml (~3.5uM). Antithrombin inhibits a broad spectrum of serine proteases including thrombin, activated forms of Factor X, Factor IX, Factor XI, Factor XII, as well as kallikrein, plasmin and urokinase. Enzyme inhibition by antithrombin occurs through proteolytic cleavage at Arg385-Ser386 and subsequent rapid formation of a stable, inactive 1/1 enzyme-antithrombin complex. Heparin has a profound accelerating effect on the inhibitory activity of antithrombin towards some enzymes. For example, the rate of inhibition of thrombin and activated Factor X is increased 1000-fold in the presence of optimal concentrations of heparin. Whereas heparin h |
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| Size | 1 kit |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | A2298-19 |
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| Order / More Info | Antithrombin (ATIII) BioAssay™ ELISA Kit (Antibodies only) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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